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Mood support; Joint health; Nervous system support
Adults with busy lifestyles seeking mood and joint support from a single daily-use amino acid derivative.
Take 1 tablet 2 to 4 times daily on an empty stomach; if sensitive, start with 1 tablet once daily and increase as tolerated.
Kosher; Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, or sesame; Produced in a facility that processes these allergens.
SAMe donates methyl groups in methylation reactions that influence neurotransmitter synthesis and cartilage matrix processes, which may support mood and joint comfort.
Caution: Take on an empty stomach for best absorption; may cause stomach upset in some people. Do not use with antidepressant medications or if you have bipolar disorder unless supervised, because it can affect neurotransmitter activity.
Label Warning: For adults only. People with bipolar depression or anxiety disorders, or those taking antidepressant medications, should use only under professional medical supervision. Consult a physician if pregnant or nursing, taking medication, or have a medical condition. Natural color variation may occur.
Who should be cautious: People with mood disorders, especially bipolar or anxiety disorders. Those using antidepressants. Individuals who are pregnant, nursing, on medications, or have underlying medical conditions should consult a healthcare provider before use.
Storage: Store in a cool, dry place after opening.
Many users report feeling brighter moods and improved emotional balance, sometimes within a week.
Several reviewers mention reduced joint discomfort and improved daily mobility.
A few users report stomach pain or mild side effects after taking the tablets.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Glucosamine and chondroitin may support joint health and flexibility, complementing SAM-e's potential benefits for joint comfort.
AI generated. Not medical advice.
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SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient minor aches and pains resulting from overexertion or strain. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support.
Take 1 tablet 2 to 4 times daily, preferably on an empty stomach.
Microcrystalline cellulose, stearic acid (vegetable source), pharmaceutical glaze, magnesium stearate (vegetable source), silicon dioxide, glycerin, sodium alginate and l-arginine.
Made and quality tested in the USA with globally sourced ingredients.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Natural color variation may occur in this product.
For adults only. Individuals with bipolar depression, anxiety disorders or taking antidepressant medications should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.
Store in a cool, dry place after opening.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Amount Per Serving | %Daily Value | |
| SAMe (S-Adenosyl-L-Methionine) (from S-Adenosyl-L-Methionine Disulfate Tosylate) | 400 mg | ** |
| ** Daily Value not established. | ||
